There’s something so comforting about pasta wrapped around creamy goodness and tender chicken. This Creamy Chicken Alfredo Lasagna Roll Ups Recipe is one of my go-to dishes when I want to impress without stressing. Trust me, these roll ups bring together all the best flavors and textures in a way that’s fun to make and impossible not to love.

A close-up of a piece of lasagna held by a wooden spatula shows three layers of wavy-edged pasta sheets with melted cheese dripping and stretching between the folds. The top layer of the pasta is golden brown with small green herb pieces sprinkled on it. Beneath this, a creamy white cheese sauce with black specks fills the inside layers, creating a rich, smooth texture that oozes out slightly. The background is soft and matches the white marbled surface below. photo taken with an iphone --ar 2:3 --v 7

Jump to:

Why You'll Love This Recipe
Ingredients & Why They Work
Make It Your Way
Step-by-Step: How I Make Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Top Tip
How to Serve Creamy Chicken Alfredo Lasagna Roll Ups Recipe
Make Ahead and Storage
Frequently Asked Questions:
Final Thoughts
Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Why You'll Love This Recipe

This recipe is like a little celebration of comfort food in every bite. I remember making it for a casual dinner party, and everyone begged for seconds. It’s rich and creamy, with shredded chicken mingling perfectly with cheesy Alfredo sauce, all rolled up in tender lasagna noodles. Plus, it’s versatile enough for weeknight dinners or special occasions alike.

Simple yet impressive: You don’t need to be a pasta pro to pull this off beautifully.
Rich, creamy flavor: The Alfredo sauce is silky smooth and perfectly seasoned for maximum comfort.
Easy to customize: You can add veggies, swap proteins, or tweak cheese amounts to suit your tastes.
Great for leftovers: This dish reheats wonderfully, making it a lifesaver for busy days.

A white rectangular baking dish holds six pieces of baked pasta arranged in two rows of three. Each piece has a top layer of melted golden-brown cheese with some spots lighter creamy white, scattered with small green herb bits. Below the cheese, there is a layer of soft, pale yellow pasta sheets folded over a creamy white sauce mixed with small visible chunks inside. The edges of the pasta are slightly ruffled, and the whole dish rests on a white marbled surface. photo taken with an iphone --ar 2:3 --v 7

Ingredients & Why They Work

The ingredients in this Creamy Chicken Alfredo Lasagna Roll Ups Recipe come together like a dream. Each one plays its part: the sauce needs the right balance of butter, garlic, and cheese for that decadent, flavorful base, while the chicken adds protein and the noodles bring it all together with tender support. Picking fresh garlic and good quality Parmesan can really take it to the next level.

Flat lay of uncooked lasagna noodles arranged in a neat stack, a few cloves of fresh garlic, a small white ceramic bowl of butter cubes, a small white ceramic bowl of all-purpose flour, a small white ceramic bowl filled with milk, a small white ceramic bowl filled with heavy whipping cream, a small white ceramic bowl of grated parmesan cheese, a small white ceramic bowl of shredded mozzarella cheese, a small white ceramic bowl of cooked shredded chicken, a small white ceramic bowl of chopped fresh parsley, two whole uncracked brown eggs, all placed symmetrically on a clean white marble surface, soft natural light, photo taken with an iPhone, professional food photography style, fresh ingredients, white ceramic bowls, no bottles, no duplicates, no utensils, no packaging --ar 2:3 --v 7 --p m7354615311229779997

Lasagna noodles: Using uncooked noodles that you boil to al dente ensures they’re sturdy enough to hold the filling without breaking.
Butter: The base for your Alfredo sauce, providing richness and that silky texture.
Garlic: Adds that familiar, warm flavor that makes the sauce sing.
All-purpose flour: This is your thickening agent, turning the sauce velvety and luscious.
Milk and heavy whipping cream: A perfect combo for creamy consistency without being too heavy or too thin.
Parmesan cheese: Key for authentic Alfredo flavor—don’t skip the parmesan or substitute with pre-grated kind to keep that melt and taste true.
Salt, pepper, and nutmeg: Seasonings that elevate the sauce beyond simple creaminess to something memorable.
Cooked shredded chicken: A great shortcut when you already have rotisserie chicken or leftovers.
Mozzarella cheese: Melts beautifully to bind everything with gooey cheese pulls.
Fresh parsley: A sprinkle on top adds color and hints of freshness to cut through the richness.

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Note: You'll find the complete list of ingredients, along with their exact measurements, in the printable recipe card at the bottom of this post.

Make It Your Way

One of the things I adore about this Creamy Chicken Alfredo Lasagna Roll Ups Recipe is how easily you can make it your own. I sometimes toss in sautéed mushrooms or spinach for an extra layer of flavor and nutrition. You could also swap chicken for turkey or even shrimp if that’s more your vibe. This recipe adapts so well, making it a real crowd-pleaser no matter your preferences.

Variation: I once made a version with sun-dried tomatoes and a pinch of red pepper flakes for a subtle kick, which became an instant favorite.

Step-by-Step: How I Make Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Step 1: Perfectly Cook the Noodles

Start by boiling your lasagna noodles with a teaspoon of salt until they’re al dente—meaning they have a little bite but aren’t mushy. I like to keep them in a pot with room temperature water after draining to stop them from sticking together. Trust me, this little step makes rolling them up so much easier later.

Step 2: Make the Creamy Alfredo Sauce

In a pan over medium heat, melt the butter and sauté minced garlic until fragrant (about a minute). Then stir in the flour, cooking it for another minute to cook off the raw taste. Slowly whisk in the milk and heavy cream, letting it simmer gently until thickened—about 2 minutes. Stir in your Parmesan cheese and seasonings until silky and smooth. If it gets too thick, just splash in a little more milk.

Step 3: Mix the Filling

Combine about a cup of your Alfredo sauce with the shredded chicken and mozzarella in a bowl. Season lightly with salt and pepper. This mix is what you'll spoon onto each noodle, so get ready to spread creamy deliciousness!

Step 4: Assemble the Roll Ups

Spread a little of the Alfredo sauce onto the bottom of your prepared baking dish to keep things from sticking and add extra flavor. Lay out each noodle, spoon the chicken mixture across it, and roll it up tightly. Place seam side down in the baking dish in a single layer.

Step 5: Bake Until Golden and Bubbling

Pour the remaining Alfredo sauce over the roll ups and sprinkle with extra mozzarella if you like cheesy tops. Bake in a preheated oven at 375°F (190°C) for about 25 to 30 minutes until bubbly and the cheese has melted beautifully with a gorgeous golden color.

Top Tip

From years of making this dish, I’ve learned a few tricks that really help nail this recipe every time. These small tips save you time and frustration, so you get more joy out of cooking and eating!

Keep noodles moist: After draining, keep them covered or in a shallow pan with room temp water until ready; this stops drying out and cracking.
Cheese quality matters: Freshly grated Parmesan melts much better and has a richer flavor than pre-grated bags, trust me on this!
Don’t skip seasoning: The Alfredo sauce brightens with a pinch of nutmeg and plenty of salt and pepper.
Even spreading: Spread filling evenly but thinly on each noodle to make rolling easier and avoid overstuffed, messy roll-ups.

How to Serve Creamy Chicken Alfredo Lasagna Roll Ups Recipe

Chicken Alfredo Lasagna Roll Ups - Serving Suggestion

Garnishes

I always finish these roll ups with a sprinkle of fresh chopped parsley — it adds a fresh pop of color and a hint of brightness that perfectly balances the richness of the sauce. Sometimes I add a little grated extra Parmesan right at the table because, why not?

Side Dishes

This pairs beautifully with crisp, garlicky green beans or a light Caesar salad to cut through the creaminess. A crunchy side of garlic bread is a natural match too—perfect for mopping up extra sauce!

Creative Ways to Present

For special occasions, I like to bake the roll ups in individual ramekins or use a decorative baking dish to make it feel extra special. Setting each roll on a plate with a drizzle of basil pesto or a few cherry tomatoes on the side makes a simple dinner look like a restaurant meal.

Make Ahead and Storage

Storing Leftovers

Leftovers are fantastic! I usually let them cool completely before storing in an airtight container in the fridge. They keep well for up to 3 days, so you can enjoy this creamy comfort with minimal effort later in the week.

Freezing

I’ve frozen these roll ups both before and after baking. Wrap them tightly in foil and place in a freezer bag. When you’re ready, thaw overnight in the fridge and bake still covered until warmed through, or bake fresh and freeze leftovers for an easy reheat.

Reheating

To reheat, cover the roll ups with foil to keep moisture in, then warm in a 350°F (175°C) oven until hot—about 15-20 minutes depending on portion size. This keeps the sauce creamy and prevents drying out better than microwaving.

Frequently Asked Questions:

Can I make these roll ups ahead of time?

Yes! You can assemble the roll ups a few hours ahead and refrigerate them covered. Just bake when ready. You can also freeze them assembled for longer storage.

What can I substitute for heavy cream?

You can use half-and-half or a mixture of whole milk and cream cheese if you want a lighter but still creamy sauce. The texture will be slightly different but still delicious.

How do I prevent the noodles from sticking?

After boiling, rinse the noodles with cool water and keep them in a bowl covered with damp kitchen towel or submerged in room temperature water to prevent sticking. Also, work with one noodle at a time when rolling.

Can I add vegetables to this recipe?

Absolutely! Sautéed spinach, mushrooms, or even roasted red peppers make fantastic additions to this dish. Just mix them into the chicken and sauce filling before rolling.

Final Thoughts

This Creamy Chicken Alfredo Lasagna Roll Ups Recipe feels like a big, warm hug on a plate every time I make it. It’s one of those recipes I’ve come back to again and again because it’s just so satisfying and approachable. You don’t have to be a culinary wizard to get rich, cheesy magic happening in your kitchen. Give it a try — I promise it’ll become one of your favorites too!